AcanR3990 qPCR: A Novel, Highly Sensitive, Bioinformatically-Informed Assay to Detect Angiostrongylus cantonensis Infections | Zendy

William J. Sears | Zendy; Yvonne Qvarnström | Zendy; Eric Dahlstrom | Zendy; Kirsten Snook | Zendy; Lisa Kaluna | Zendy; Vojtěch Baláž | Zendy; Barbora Fecková | Zendy; Jan Šlapeta | Zendy; David Modrý | Zendy; Susan I. Jarvi | Zendy; Thomas B. Nutman | Zendy

Open Access

AcanR3990 qPCR: A Novel, Highly Sensitive, Bioinformatically-Informed Assay to Detect Angiostrongylus cantonensis Infections

Author(s) -

William J. Sears,

Yvonne Qvarnström,

Eric Dahlstrom,

Kirsten Snook,

Lisa Kaluna,

Vojtěch Baláž,

Barbora Fecková,

Jan Šlapeta,

David Modrý,

Susan I. Jarvi,

Thomas B. Nutman

Publication year - 2020

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciaa1791

Subject(s) - angiostrongylus cantonensis , lungworm , angiostrongyliasis , biology , toxocariasis , toxocara cati , genomic dna , paratenic , primer (cosmetics) , helminths , zoology , dna , genetics , chemistry , organic chemistry

Angiostrongylus cantonensis (Ac), or the rat lungworm, is a major cause of eosinophilic meningitis. Humans are infected by ingesting the 3rd stage larvae from primary hosts, snails, and slugs, or paratenic hosts. The currently used molecular test is a qPCR assay targeting the ITS1 rDNA region (ITS1) of Ac.

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