Major Adverse Cardiovascular Events During Invasive Pneumococcal Disease Are Serotype Dependent | Zendy

Hector F. Africano | Zendy; Cristian C. Serrano-Mayorga | Zendy; Paula C. Ramirez-Valbuena | Zendy; Ingrid G. Bustos | Zendy; Alirio Bastidas | Zendy; Hernán Vargas | Zendy; Sandra L. GomezPerez | Zendy; Alejandro Rodríguez | Zendy; Carlos J. Orihuela | Zendy; Luis Felipe Reyes | Zendy

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Major Adverse Cardiovascular Events During Invasive Pneumococcal Disease Are Serotype Dependent

Author(s) -

Hector F. Africano,

Cristian C. Serrano-Mayorga,

Paula C. Ramirez-Valbuena,

Ingrid G. Bustos,

Alirio Bastidas,

Hernán Vargas,

Sandra L. GomezPerez,

Alejandro Rodríguez,

Carlos J. Orihuela,

Luis Felipe Reyes

Publication year - 2020

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciaa1427

Subject(s) - mace , medicine , bacteremia , retrospective cohort study , streptococcus pneumoniae , serotype , myocardial infarction , odds ratio , community acquired pneumonia , confidence interval , pneumonia , immunology , percutaneous coronary intervention , microbiology and biotechnology , antibiotics , biology

Up to 30% of patients admitted to hospitals with invasive pneumococcal disease (IPD) experience major adverse cardiovascular event (MACE) including new/worsening heart failure, new/worsening arrhythmia, and/or myocardial infarction. Streptococcus pneumoniae (Spn) is the most frequently isolated bacterial pathogen among community-acquired pneumonia (CAP) patients and the only etiological agent linked independently to MACE. Nevertheless, no clinical data exist identifying which serotypes of Spn are principally responsible for MACE.

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