Open AccessHuman Immunodeficiency Virus (HIV) Drug Resistance, Phylogenetic Analysis, and Superinfection Among Men Who Have Sex with Men and Transgender Women in Sub-Saharan Africa: HIV Prevention Trials Network (HPTN) 075 Study
Author(s) -
Mariya V. Sivay,
Philip J. Palumbo,
Yinfeng Zhang,
Vanessa Cummings,
Xingzhong Guo,
Erica L. Hamilton,
Laura McKinstry,
Arthur Ogendo,
Noel Kayange,
Ravindre Panchia,
Karen Dominguez,
Ying Qing Chen,
Theodorus Sandfort,
Susan H. Eshleman
Publication year - 2020
Publication title -
clinical infectious diseases/clinical infectious diseases (online. university of chicago. press)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciaa1136
Subject(s) - men who have sex with men , superinfection , virology , resistance mutation , medicine , transmission (telecommunications) , genotyping , drug resistance , biology , human immunodeficiency virus (hiv) , immunology , genotype , virus , genetics , polymerase chain reaction , syphilis , reverse transcriptase , electrical engineering , gene , engineering
The HIV Prevention Trials Network (HPTN) 075 study evaluated the feasibility of enrolling and retaining men who have sex with men (MSM) and transgender women (TGW) from Kenya, Malawi, and South Africa. During the study follow-up, 21 participants acquired human immunodeficiency virus (HIV) (seroconverters). We analyzed HIV subtype diversity, drug resistance, transmission dynamics, and HIV superinfection data among MSM and TGW enrolled in HPTN 075.