Open AccessCompositional Flux Within the Intestinal Microbiota and Risk for Bloodstream Infection With Gram-negative Bacteria
Author(s) -
Igor Stoma,
Eric R. Littmann,
Jonathan U. Peled,
Sergío Giralt,
Marcel R.M. van den Brink,
Eric G. Pamer,
Ying Taur
Publication year - 2020
Publication title -
clinical infectious diseases/clinical infectious diseases (online. university of chicago. press)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciaa068
Subject(s) - microbiology and biotechnology , colonization , feces , medicine , enterobacter , gut flora , pseudomonas aeruginosa , gram negative bacteria , biology , bacteria , immunology , escherichia coli , gene , biochemistry , genetics
Gram-negative bloodstream infections (BSIs) represent a significant complication facing allogeneic hematopoietic cell transplant (allo-HCT) recipients, as a result of intestinal translocation during neutropenia. In this study we sought to better understand how the composition of the intestinal microbiota is connected to risk of gram-negative BSIs, expanding on our prior work in these patients.