A Western-Type Dietary Pattern Induces an Atherogenic Gene Expression Profile in the Coronary Arteries of the Ossabaw Pig | Zendy

Maura E. Walker | Zendy; Nirupa R. Matthan | Zendy; Stefania LamonFava | Zendy; Gloria SolanoAguilar | Zendy; Saebyeol Jang | Zendy; Sukla Lakshman | Zendy; Aleksey Molokin | Zendy; Joseph F. Urban | Zendy; Tyler Faits | Zendy; W. Evan Johnson | Zendy; Alice H. Lichtenstein | Zendy

Open Access

A Western-Type Dietary Pattern Induces an Atherogenic Gene Expression Profile in the Coronary Arteries of the Ossabaw Pig

Author(s) -

Maura E. Walker,

Nirupa R. Matthan,

Stefania LamonFava,

Gloria SolanoAguilar,

Saebyeol Jang,

Sukla Lakshman,

Aleksey Molokin,

Joseph F. Urban,

Tyler Faits,

W. Evan Johnson,

Alice H. Lichtenstein

Publication year - 2019

Publication title -

current developments in nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.904

H-Index - 14

ISSN - 2475-2991

DOI - 10.1093/cdn/nzz023

Subject(s) - transcriptome , medicine , statin , downregulation and upregulation , artery , candidate gene , gene expression , endocrinology , cholesterol , coronary artery disease , cardiology , biology , gene , genetics

These data suggest that a WD induces alterations in the transcriptome of the coronary artery consistent with an inflammatory atherogenic phenotype in the Ossabaw pig with no significant modification by concurrent statin therapy.

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