Non-motor outcomes depend on location of neurostimulation in Parkinson’s disease | Zendy

Jan Niklas PetrySchmelzer | Zendy; Max Krause | Zendy; Till A. Dembek | Zendy; Andreas Horn | Zendy; Julian Evans | Zendy; Keyoumars Ashkan | Zendy; Alexandra Rizos | Zendy; Monty Silverdale | Zendy; Wibke Schumacher | Zendy; Carolin Sack | Zendy; Philipp Alexander Loehrer | Zendy; Gereon R. Fink | Zendy; Erich Talamoni Fonoff | Zendy; Pablo MartínezMartin | Zendy; Angelo Antonini | Zendy; Michael T. Barbe | Zendy; Veerle VisserVandewalle | Zendy; К. Ray Chaudhuri | Zendy; Lars Timmermann | Zendy; Haidar S. Dafsari | Zendy; Per Odin | Zendy; Anette Schrag | Zendy; Daniel Weintraub | Zendy; Paolo Barone | Zendy; David J. Brooks | Zendy; Richard G. Brown | Zendy; Peter Jenner | Zendy; Beomseok Jeon | Zendy; Kelly E. Lyons | Zendy; Nicola Pavese | Zendy; Marios Politis | Zendy; Ronald B. Postuma | Zendy; Anthony H.V. Schapira | Zendy; Fabrizio Stocchi | Zendy; Yoshio Tsuboi | Zendy; Anna Sauerbier | Zendy

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Non-motor outcomes depend on location of neurostimulation in Parkinson’s disease

Author(s) -

Jan Niklas PetrySchmelzer,

Max Krause,

Till A. Dembek,

Andreas Horn,

Julian Evans,

Keyoumars Ashkan,

Alexandra Rizos,

Monty Silverdale,

Wibke Schumacher,

Carolin Sack,

Philipp Alexander Loehrer,

Gereon R. Fink,

Erich Talamoni Fonoff,

Pablo MartínezMartin,

Angelo Antonini,

Michael T. Barbe,

Veerle VisserVandewalle,

К. Ray Chaudhuri,

Lars Timmermann,

Haidar S. Dafsari,

Per Odin,

Anette Schrag,

Daniel Weintraub,

Paolo Barone,

David J. Brooks,

Richard G. Brown,

Peter Jenner,

Beomseok Jeon,

Kelly E. Lyons,

Nicola Pavese,

Marios Politis,

Ronald B. Postuma,

Anthony H.V. Schapira,

Fabrizio Stocchi,

Yoshio Tsuboi,

Anna Sauerbier

Publication year - 2019

Publication title -

brain

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.142

H-Index - 336

eISSN - 1460-2156

pISSN - 0006-8950

DOI - 10.1093/brain/awz285

Subject(s) - neurostimulation , parkinson's disease , motor symptoms , physical medicine and rehabilitation , medicine , neuroscience , disease , psychology , stimulation

Deep brain stimulation of the subthalamic nucleus improves non-motor symptoms in Parkinson’s disease, but with considerable inter-individual variability. Petry-Schmelzer et al. show that neurostimulation in specific subregions of the subthalamic nucleus has differential effects on mood/apathy, attention/memory and sleep-related outcomes. Neurostimulation could thus be tailored to patients’ individual non-motor profiles.

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