A year-long immune profile of the systemic response in acute stroke survivors
Author(s) -
Amy S. Tsai,
Kacey Berry,
Maxime Beneyto,
Dyani Gaudillière,
Edward A. Ganio,
Anthony Culos,
Mohammad Sajjad Ghaemi,
Benjamin Choisy,
Karim Djebali,
Jakob Einhaus,
Basile Bertrand,
Athena Tanada,
Natalie Stanley,
Ramin Fallahzadeh,
Quentin Baca,
Lisa N. Quach,
Elizabeth Osborn,
Lauren L. Drag,
Maarten G. Lansberg,
Martin S. Angst,
Brice Gaudillière,
Marion S. Buckwalter,
Nima Aghaeepour
Publication year - 2019
Publication title -
brain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.142
H-Index - 336
eISSN - 1460-2156
pISSN - 0006-8950
DOI - 10.1093/brain/awz022
Subject(s) - stroke (engine) , immune system , medicine , acute stroke , immunology , tissue plasminogen activator , mechanical engineering , engineering
Whether the systemic immune response to stroke contributes to long-term disability is unclear. Using deep immune profiling of peripheral blood over a one-year period following ischaemic stroke, Tsai et al. identify three immunological phases characterized by sequential engagement of innate and adaptive immune compartments, which correlate with post-stroke cognitive trajectories.
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