The non-motor syndrome of primary dystonia: clinical and pathophysiological implications | Zendy

María Stamelou | Zendy; Mark J. Edwards | Zendy; Mark Hallett | Zendy; Kailash P. Bhatia | Zendy

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The non-motor syndrome of primary dystonia: clinical and pathophysiological implications

Author(s) -

María Stamelou,

Mark J. Edwards,

Mark Hallett,

Kailash P. Bhatia

Publication year - 2011

Publication title -

brain

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.142

H-Index - 336

eISSN - 1460-2156

pISSN - 0006-8950

DOI - 10.1093/brain/awr224

Subject(s) - dystonia , neuroscience , pathophysiology , movement disorders , psychology , physical medicine and rehabilitation , cognition , medicine , pathology , disease

Dystonia is typically considered a movement disorder characterized by motor manifestations, primarily involuntary muscle contractions causing twisting movements and abnormal postures. However, growing evidence indicates an important non-motor component to primary dystonia, including abnormalities in sensory and perceptual functions, as well as neuropsychiatric, cognitive and sleep domains. Here, we review this evidence and discuss its clinical and pathophysiological implications.

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