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Distinct patterns of structural damage underlie working memory and reasoning deficits after traumatic brain injury
Author(s) -
Amy Jolly,
Gregory Scott,
David Sharp,
Adam Hampshire
Publication year - 2020
Publication title -
brain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.142
H-Index - 336
eISSN - 1460-2156
pISSN - 0006-8950
DOI - 10.1093/brain/awaa067
Subject(s) - cognition , working memory , psychology , connectome , white matter , traumatic brain injury , neuroscience , diffusion mri , effects of sleep deprivation on cognitive performance , cognitive psychology , connectomics , diffuse axonal injury , medicine , functional connectivity , magnetic resonance imaging , psychiatry , radiology
The heterogeneity of patterns of diffuse axonal injury and cognitive impairment after TBI presents a challenge for predicting long-term outcomes. Using diffusion-weighted imaging and network analyses, Jolly et al. show that impairments in working memory and reasoning correlate with distinct patterns of structural damage.

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