Open AccessSimRVSequences: an R package to simulate genetic sequence data for pedigrees
Author(s) -
Christiieuwoudt,
Angela BrooksWilson,
Jinko Graham
Publication year - 2019
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btz881
Subject(s) - pedigree chart , r package , sequence (biology) , sample (material) , computer science , data mining , genetics , biology , programming language , gene , chemistry , chromatography
We present the R package SimRVSequences to simulate sequence data for pedigrees. SimRVSequences allows for simulations of large numbers of single-nucleotide variants (SNVs) and scales well with increasing numbers of pedigrees. Users provide a sample of pedigrees and SNV data from a sample of unrelated individuals.