Open AccessAn algorithm for identification of bacterial selenocysteine insertion sequence elements and selenoprotein genes
Author(s) -
Yan Zhang,
Vadim N. Gladyshev
Publication year - 2005
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bti400
Subject(s) - selenocysteine , selenoprotein , biology , computational biology , genetics , insertion sequence , gene , genome , stop codon , biochemistry , glutathione , transposable element , glutathione peroxidase , cysteine , enzyme
Incorporation of selenocysteine (Sec) into proteins in response to UGA codons requires a cis-acting RNA structure, Sec insertion sequence (SECIS) element. Whereas SECIS elements in Escherichia coli are well characterized, a bacterial SECIS consensus structure is lacking.
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