The minimizer Jaccard estimator is biased and inconsistent | Zendy

Mahdi Belbasi | Zendy; Antonio Blanca | Zendy; Robert S. Harris | Zendy; David Koslicki | Zendy; Paul Medvedev | Zendy

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The minimizer Jaccard estimator is biased and inconsistent

Author(s) -

Mahdi Belbasi,

Antonio Blanca,

Robert S. Harris,

David Koslicki,

Paul Medvedev

Publication year - 2022

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btac244

Subject(s) - jaccard index , estimator , computer science , limit (mathematics) , scalability , algorithm , scripting language , data mining , statistics , mathematics , pattern recognition (psychology) , artificial intelligence , mathematical analysis , database , operating system

Sketching is now widely used in bioinformatics to reduce data size and increase data processing speed. Sketching approaches entice with improved scalability but also carry the danger of decreased accuracy and added bias. In this article, we investigate the minimizer sketch and its use to estimate the Jaccard similarity between two sequences.

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