LinkExplorer: predicting, explaining and exploring links in large biomedical knowledge graphs
Author(s) -
Simon Ott,
Adriano Barbosa-Silva,
Matthias Samwald
Publication year - 2022
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btac068
Subject(s) - suite , computer science , source code , documentation , black box , software , interface (matter) , machine learning , code (set theory) , data mining , data science , information retrieval , theoretical computer science , artificial intelligence , programming language , set (abstract data type) , archaeology , bubble , maximum bubble pressure method , parallel computing , history
Machine learning algorithms for link prediction can be valuable tools for hypothesis generation. However, many current algorithms are black boxes or lack good user interfaces that could facilitate insight into why predictions are made. We present LinkExplorer, a software suite for predicting, explaining and exploring links in large biomedical knowledge graphs. LinkExplorer integrates our novel, rule-based link prediction engine SAFRAN, which was recently shown to outcompete other explainable algorithms and established black-box algorithms. Here, we demonstrate highly competitive evaluation results of our algorithm on multiple large biomedical knowledge graphs, and release a web interface that allows for interactive and intuitive exploration of predicted links and their explanations.
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