Open AccessExTraMapper: exon- and transcript-level mappings for orthologous gene pairs
Author(s) -
Abhijit Chakraborty,
Ferhat Ay,
Ramana V. Davuluri
Publication year - 2021
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btab393
Subject(s) - exon , gene , genetics , computational biology , biology , computer science
Access to large-scale genomics and transcriptomics data from various tissues and cell lines allowed the discovery of wide-spread alternative splicing events and alternative promoter usage in mammalians. Between human and mouse, gene-level orthology is currently present for nearly 16k protein-coding genes spanning a diverse repertoire of over 200k total transcript isoforms.