Open AccessEvidence-based development of a nephrotoxic medication list to screen for acute kidney injury risk in hospitalized children
Author(s) -
Elizabeth Goswami,
Richard K. Ogden,
William E. Bennett,
Stuart L. Goldstein,
Richard Hackbarth,
Michael J. Somers,
Karyn Yonekawa,
Jason Misurac
Publication year - 2019
Publication title -
american journal of health-system pharmacy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.487
H-Index - 96
eISSN - 1535-2900
pISSN - 1079-2082
DOI - 10.1093/ajhp/zxz203
Subject(s) - nephrotoxicity , medicine , acute kidney injury , intensive care medicine , medline , family medicine , medical emergency , kidney , political science , law
Medications are commonly associated with acute kidney injury (AKI). However, in both clinical practice and research, consideration of specific medications as nephrotoxic varies widely. The Nephrotoxic Injury Negated by Just-in-time Action quality improvement collaborative was formed to focus on prevention or reduction of nephrotoxic medication-associated AKI in noncritically ill hospitalized children. However, there were discrepancies among institutions as to which medications should be considered nephrotoxic. The collaborative convened a Nephrotoxic Medication (NTMx) Subcommittee to develop a consensus for the classification of nephrotoxic medications.