De Novo Identification and Visualization of Important Cell Populations for Classic Hodgkin Lymphoma Using Flow Cytometry and Machine Learning
Author(s) -
Paul D. Simonson,
Yue Wu,
David Wu,
Jonathan R. Fromm,
Aaron Lee
Publication year - 2021
Publication title -
american journal of clinical pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.859
H-Index - 128
eISSN - 1943-7722
pISSN - 0002-9173
DOI - 10.1093/ajcp/aqab076
Subject(s) - flow cytometry , identification (biology) , lymphoma , visualization , computational biology , computer science , biology , pathology , artificial intelligence , medicine , immunology , botany
Automated classification of flow cytometry data has the potential to reduce errors and accelerate flow cytometry interpretation. We desired a machine learning approach that is accurate, is intuitively easy to understand, and highlights the cells that are most important in the algorithm's prediction for a given case.
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