Loss of major nutrient sensing and signaling pathways suppresses starvation lethality in electron transport chain mutants
Author(s) -
Alisha G. Lewis,
Robert Caldwell,
Jason V. Rogers,
Maria Ingaramo,
Rebecca Y. Wang,
Ilya Soifer,
David G. Hendrickson,
R. Scott McIsaac,
David Botstein,
Patrick A. Gibney
Publication year - 2021
Publication title -
molecular biology of the cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.463
H-Index - 225
eISSN - 1939-4586
pISSN - 1059-1524
DOI - 10.1091/mbc.e21-06-0314
Subject(s) - biology , microbiology and biotechnology , mutant , phenotype , signal transduction , suppressor , nutrient sensing , mitochondrion , metabolic pathway , mutation , saccharomyces cerevisiae , oxidative phosphorylation , synthetic lethality , gene , yeast , transport protein , socs6 , cell physiology , cell signaling , starvation , cell , starvation response , flux (metallurgy) , genetic screen , genetics , biochemistry , suppressor mutation , dna damage , atp synthase , fungal protein , membrane transport protein , regulation of gene expression , mechanism (biology) , cell membrane , membrane protein , biological pathway , metabolism , homeostasis
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