Open AccessGenomic Characterization of Crimean–Congo Hemorrhagic Fever Virus inHyalommaTick from Spain, 2014
Author(s) -
Maria N.B. Cajimat,
Sergio E. Rodriguez,
Isolde Schuster,
Daniele M. Swetnam,
Thomas G. Ksiazek,
M. Habela,
Anabel Negredo,
Agustı́n Estrada-Peña,
Alan D.T. Barrett,
Dennis A. Bente
Publication year - 2017
Publication title -
vector borne and zoonotic diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.839
H-Index - 73
eISSN - 1557-7759
pISSN - 1530-3667
DOI - 10.1089/vbz.2017.2190
Subject(s) - hyalomma , crimean–congo hemorrhagic fever , tick , virology , biology , tick borne disease , virus , ixodidae
Crimean-Congo hemorrhagic fever (CCHF) is a severe tick-borne disease caused by CCHF virus (CCHFV). Ticks in the genus Hyalomma are the main vectors and reservoirs of CCHFV. In Spain, CCHFV was first detected in Hyalomma ticks from Cáceres in 2010. Subsequently, two autochthonous CCHF cases were reported in August 2016. In this study, we describe the characterization of the CCHFV genome directly from Hyalomma lusitanicum collected in Cáceres in 2014. Phylogenetic analyses reveal a close relationship with clade III strains from West Africa, with an estimated divergence time of 50 years. The results of this work suggest that CCHFV has been circulating in Spain for some time, and most likely originated from West Africa.