Open AccessDoes Anatomic Resection Get More Benefits than Wedge Hepatectomy on the Prognosis for pT3 Unsuspected Gallbladder Cancer?
Author(s) -
Lianghe Yu,
Bo Yuan,
Xiaohui Fu,
Wenlong Yu,
Jian Liu,
Yongjie Zhang
Publication year - 2019
Publication title -
journal of laparoendoscopic and advanced surgical techniques. part a/journal of laparoendoscopic and advanced surgical techniques
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.588
H-Index - 59
eISSN - 1557-9034
pISSN - 1092-6429
DOI - 10.1089/lap.2018.0690
Subject(s) - medicine , hepatoduodenal ligament , hepatectomy , wedge resection , lymphadenectomy , surgery , gallbladder , gallbladder cancer , propensity score matching , retrospective cohort study , survival analysis , resection , cancer
Background: Re-radical surgery is the only curative therapy for unsuspected gallbladder carcinoma (UGC). The aim of this study was to compare prognosis of pT3 UGC patients receiving anatomic hepatectomy (AH) or wedge hepatectomy (WH) combined with en bloc local-regional lymphadenectomy of the hepatoduodenal ligament using propensity score-matching (PSM) analysis. Materials and Methods: A retrospective study was carried out on 81 consecutive pT3 UGC patients who underwent radical re-resection at Eastern Hepatobiliary Surgery Hospital from 2006 to 2015. Overall survival (OS) was estimated using Kaplan-Meier method. The difference in OS between the AH and WH groups was analyzed using the log-rank test and the PSM method. Result: The AH and WH groups showed no significant difference in OS ( P > .05) by either log-rank test or PSM analysis. Conclusions: Both AH and WH radical re-resections are effective treatments for UCG patients with pT3 tumors.