Open AccessAbsorption and Clearance of Pharmaceutical Aerosols in the Human Nose: Development of a CFD Model
Author(s) -
Alex D. Rygg,
P. Worth Longest
Publication year - 2016
Publication title -
journal of aerosol medicine and pulmonary drug delivery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.678
H-Index - 68
eISSN - 1941-2703
pISSN - 1941-2711
DOI - 10.1089/jamp.2015.1252
Subject(s) - particle deposition , mucociliary clearance , absorption (acoustics) , nasal cavity , aerosol , chemistry , deposition (geology) , particle (ecology) , biomedical engineering , nose , particle size , materials science , medicine , surgery , lung , composite material , paleontology , oceanography , organic chemistry , sediment , biology , geology
The objective of this study was to develop a computational fluid dynamics (CFD) model to predict the deposition, dissolution, clearance, and absorption of pharmaceutical particles in the human nasal cavity.