Open AccessGenetic Analysis of the ZNF512B, SLC41A1, and ALDH2 Polymorphisms in Parkinson's Disease in the Iranian Population
Author(s) -
Faranak Madadi,
Mahmoud Shekari Khaniani,
Ehsan Esmaili Shandiz,
Hormoz Ayromlou,
Safa Najmi,
Babak Emamalizadeh,
Shaghayegh Taghavi,
Javad Jamshidi,
Abbas Tafakhori,
Gholam Ali Shahidi,
Hossein Darvish
Publication year - 2016
Publication title -
genetic testing and molecular biomarkers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.405
H-Index - 47
eISSN - 1945-0265
pISSN - 1945-0257
DOI - 10.1089/gtmb.2016.0133
Subject(s) - allele , genotype , genetics , parkinson's disease , single nucleotide polymorphism , polymorphism (computer science) , biology , genetic association , allele frequency , population , disease , case control study , medicine , gene , environmental health
Parkinson's disease (PD) is one of the most common neurodegenerative disorders; its etiology includes both genetic and environmental factors and their interactions. The ZNF512B, SLC41A1, and ALDH2 genes have recently been identified as contributing to PD. In this study we investigated the association of alleles of these genes with PD in the Iranian population.