
Efficient and Fast Generation of Relevant Disease Mouse Models by In Vitro and In Vivo Gene Editing of Zygotes
Author(s) -
Raquel Sánchez-Baltasar,
Aida García-Torralba,
Virginia Nieto-Romero,
Angustias Page,
Andrea Molinos-Vicente,
Sergio López-Manzaneda,
Isabel Ojeda-Pérez,
Ángel Ramı́rez,
Manuel Navarro,
José C. Segovia,
María GarcíaBravo
Publication year - 2022
Publication title -
the crispr journal
Language(s) - English
Resource type - Journals
eISSN - 2573-1602
pISSN - 2573-1599
DOI - 10.1089/crispr.2022.0013
Subject(s) - electroporation , genome editing , biology , in vivo , in vitro , gene , zygote , smarca4 , microbiology and biotechnology , ribonucleoprotein , genetics , computational biology , genome , rna , epigenetics , embryogenesis , chromatin remodeling