A Meta-Analysis of gRNA Library Screens Enables an Improved Understanding of the Impact of gRNA Folding and Structural Stability on CRISPR-Cas9 Activity
Author(s) -
Eirik A. Moreb,
Michael Lynch
Publication year - 2022
Publication title -
the crispr journal
Language(s) - English
Resource type - Journals
eISSN - 2573-1602
pISSN - 2573-1599
DOI - 10.1089/crispr.2021.0084
Subject(s) - crispr , guide rna , computational biology , chemistry , folding (dsp implementation) , computer science , cas9 , biology , biochemistry , gene , engineering , electrical engineering
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