Increased Efficiency for Biallelic Mutations of theCCR5Gene by CRISPR-Cas9 Using Multiple Guide RNAs As a Novel Therapeutic Option for Human Immunodeficiency Virus
Author(s) -
Dong Lin,
Stefan H. Scheller,
Madeline M. Robinson,
Reza Izadpanah,
Eckhard Alt,
Stephen E. Braun
Publication year - 2021
Publication title -
the crispr journal
Language(s) - English
Resource type - Journals
eISSN - 2573-1602
pISSN - 2573-1599
DOI - 10.1089/crispr.2020.0019
Subject(s) - crispr , frameshift mutation , subgenomic mrna , biology , guide rna , genetics , virology , cas9 , indel , gene , mutation , gene knockout , genotype , single nucleotide polymorphism
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom