Open AccessAptaBlocks Online: A Web-Based Toolkit for the In Silico Design of Oligonucleotide Sticky Bridges
Author(s) -
Jan Hoinka,
Yijie Wang,
Teresa M. Przytycka
Publication year - 2020
Publication title -
journal of computational biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.585
H-Index - 95
eISSN - 1557-8666
pISSN - 1066-5277
DOI - 10.1089/cmb.2019.0470
Subject(s) - in silico , oligonucleotide , computer science , interface (matter) , web application , software , software engineering , graphical user interface , world wide web , computational biology , biology , programming language , operating system , dna , genetics , gene , biochemistry , bubble , maximum bubble pressure method
The AptaBlocks Web Interface is focused on providing graphical, intuitive, and platform-independent access to AptaBlocks, an experimentally validated algorithmic approach for the in silico design of oligonucleotide sticky bridges. The availability of AptaBlocks online to the nucleic acid research community at large makes this software a highly effective tool for accelerating the design and development of novel oligonucleotide-based drugs and other biotechnologies.