AptaBlocks Online: A Web-Based Toolkit for the In Silico Design of Oligonucleotide Sticky Bridges | Zendy

Jan Hoinka | Zendy; Yijie Wang | Zendy; Teresa M. Przytycka | Zendy

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AptaBlocks Online: A Web-Based Toolkit for the In Silico Design of Oligonucleotide Sticky Bridges

Author(s) -

Jan Hoinka,

Yijie Wang,

Teresa M. Przytycka

Publication year - 2020

Publication title -

journal of computational biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.585

H-Index - 95

eISSN - 1557-8666

pISSN - 1066-5277

DOI - 10.1089/cmb.2019.0470

Subject(s) - in silico , oligonucleotide , computer science , software engineering , interface (matter) , web application , software , user interface , graphical user interface , world wide web , biology , programming language , operating system , dna , biochemistry , genetics , bubble , maximum bubble pressure method , gene

The AptaBlocks Web Interface is focused on providing graphical, intuitive, and platform-independent access to AptaBlocks, an experimentally validated algorithmic approach for the in silico design of oligonucleotide sticky bridges. The availability of AptaBlocks online to the nucleic acid research community at large makes this software a highly effective tool for accelerating the design and development of novel oligonucleotide-based drugs and other biotechnologies.

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