English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Periodontitis noted as dental care disease, which occur the inflammatory process in the teeth tissues surrounding which has the response to bacterial accumulation. The main objectives of the present investigations were to improve the multifunctional nanocomposite with PLGA@fluorapatite and enhance the bactericidal inhibitory efficiency against periodontitis-related pathogens. The peptide modified fluorapatite@PLGA nanocomposite were synthesized and physico-chemically characterized. The observed analytical results demonstrated rod-like nanoparticles formation with favorable human cell compatibility and toxicity against bacterial pathogens. In addition, the use of FA and PLGA dual agents in the composite achieved the greatest reduction in the biofilm growth and the metabolic activity of polysaccharide production. The CFU count in the biofilms was reduced by nearly 3 orders for periodontal pathogens. Therefore, the new modified peptide PLGA-FA composite promising in the root caries restorations to inhibit periodontitis related pathogens.

materials research express

Practical evaluations of bioactive peptide-modified Fluorapatite/PLGA multifunctional nano-clustery composite against for root caries restorations to inhibit periodontitis-related pathogens in periodontitis care