Open AccessAn EXAFS spectroscopic study of Europium (III) complexation with dafone
Author(s) -
Abdolhamed Shahedi,
J. Rahighi,
Mohammad Agha Bolorizadeh
Publication year - 2020
Publication title -
materials research express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.383
H-Index - 35
ISSN - 2053-1591
DOI - 10.1088/2053-1591/abad05
Subject(s) - europium , chemistry , extended x ray absorption fine structure , crystallography , ligand (biochemistry) , natural bond orbital , nuclear chemistry , inorganic chemistry , absorption spectroscopy , molecule , organic chemistry , ion , physics , biochemistry , receptor , quantum mechanics
An extended x-ray absorption fine structure (EXAFS) for L III Eu crystal edge at 6977 eV energy was studied on an original complex based on europium. The ligand was coordinated entirely with respect to europium atom for [Eu(dafone) 2 Cl 2 .(H 2 O) 2 ](Cl)(H 2 O), where dafone is 4,5-diazafluoren-9-one. The EXAFS spectra showed close-neighbor correlations between europium and nitrogen atoms as well as to the adjoining carbon backbones on macrocyclic cages, which resulted in the bond lengths, the Debye-Waller factor, and coordination numbers. The Eu (III) complex in vitro antibacterial efficacy on a set of Gram-negative bacteria and Gram-positive bacteria showed that the complex displays marked antibacterial behavior. The minimum complex inhibitory concentrations showed that the Eu complex displays significantly higher antibacterial impact on conventional Staphylococcus aureus and Escherichia coli bacterial strains compared to those of silver sulfadiazine and europium nitrate. The Eu (III) bacterial inhibitions are closely linked to relevant DNA binding affinities.