Open AccessA synthesis of polyethylene glycol (PEG)-coated magnetite Fe3O4 nanoparticles and their characteristics for enhancement of biosensor
Author(s) -
Ganesha Antarnusa,
Edi Suharyadi
Publication year - 2020
Publication title -
materials research express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.383
H-Index - 35
ISSN - 2053-1591
DOI - 10.1088/2053-1591/ab8bef
Subject(s) - polyethylene glycol , crystallite , materials science , nanoparticle , peg ratio , fourier transform infrared spectroscopy , coercivity , magnetite , chemical engineering , transmission electron microscopy , spinel , analytical chemistry (journal) , nuclear chemistry , nanotechnology , chemistry , chromatography , metallurgy , physics , finance , condensed matter physics , economics , engineering
The magnetite Fe 3 O 4 nanoparticles were synthesized by using chemical co-precipitation method and these nanoparticles were successfully coated by polyethylene glycol (PEG) with variation concentrations of PEG. The magnetite Fe 3 O 4 nanoparticles used as a bimolecular label (nano-tags), exhibiting a soft magnetic behavior with magnetization ( M s ) of 77.16 emu g −1 and coercivity ( H c ) of 50 Oe respectively. The polyethylene glycol (PEG) was used as a biocompatible polymer. The x-ray diffraction (XRD) patterns of the Fe 3 O 4 showed that Fe 3 O 4 was well crystallized. It also confirmed the existence of invers spinel. The diffraction peak of 35.4° was used to calculate the crystallite size. The estimation of Fe 3 O 4 average crystallite size is 12 nm, while the PEG-coated Fe 3 O 4 nanoparticles is 8.6 nm. The transmission electron microscopy (TEM) images of Fe 3 O 4 showed that the morphology of magnetite Fe 3 O 4 nanoparticle is spherical in shape with uniform grain size and good dispersibility despite the agglomeration it found in some place. The addition of PEG can decrease the agglomeration and reduce the particle size. The existence of PEG layer on Fe 3 O 4 was confirmed by Fourier transform infrared (FTIR) spectroscopy. The result of Vibrating Sample Magnetometer (VSM) showed that saturation magnetization ( M s ) of Fe 3 O 4 nanoparticles decreased from 77.16 to 37.15 emu g −1 with the increase of PEG weight from 0% to 50%. Such Fe 3 O 4 nanoparticles with favorable size and tunable magnetic properties are promising biosensor applications.