Enhanced drug efficiency of doped ZnO–GO (graphene oxide) nanocomposites, a new gateway in drug delivery systems (DDSs) | Zendy

H. Afzal | Zendy; Muhammad Ikram | Zendy; Salamat Ali | Zendy; Anum Shahzadi | Zendy; Muhammad Aqeel | Zendy; Ali Haider | Zendy; Muhammad Imran | Zendy; Sajjad Ali | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Enhanced drug efficiency of doped ZnO–GO (graphene oxide) nanocomposites, a new gateway in drug delivery systems (DDSs)

Author(s) -

H. Afzal,

Muhammad Ikram,

Salamat Ali,

Anum Shahzadi,

Muhammad Aqeel,

Ali Haider,

Muhammad Imran,

Sajjad Ali

Publication year - 2019

Publication title -

materials research express

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.383

H-Index - 35

ISSN - 2053-1591

DOI - 10.1088/2053-1591/ab61ae

Subject(s) - materials science , graphene , doping , nanorod , oxide , nanocomposite , nanotechnology , drug delivery , chemical engineering , nanoparticle , dissolution , absorption spectroscopy , optoelectronics , optics , engineering , metallurgy , physics

Graphene oxide (GO) nanosheets were doped to zinc oxide (ZnO) nanoparticles using a facile chemical deposition method. X-ray diffraction (XRD) confirmed the presence of hexagonal structure and increased peaks broadening upon doping. Undoped and ZnO doped GO sheets showed morphology like nanoparticles, nanorods and flakes were observed under transmission and field emission electron microscopies respectively. An increase in absorption was observed in absorption spectra upon doping recorded via UV-visible spectroscopy. The hydrogen bonding between functional groups of GO and ZnO is responsible for limiting maximum drug loading efficiency. GO doped ZnO has higher drug loading efficiency of about 89% compared to ZnO (82%) and this trend reverse in drug releasing process. This study will provide an efficient design of the drug delivery system for dissolution enhancement according to the required drug release.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research