Open AccessEco-Friendly One Pot Synthesis Of Triazole Containing Pyrrolopyridine Derivatives Using PEG-600
Author(s) -
Bhupender Kumar,
K. Srivani,
M. Ramesh,
M. Thirumala Chary,
Laxminarayana Eppakayala
Publication year - 2020
Publication title -
iop conference series. materials science and engineering
Language(s) - English
Resource type - Journals
eISSN - 1757-899X
pISSN - 1757-8981
DOI - 10.1088/1757-899x/981/2/022096
Subject(s) - environmentally friendly , peg ratio , propargyl bromide , chemistry , peg 400 , solvent , bromide , propargyl , triazole , component (thermodynamics) , combinatorial chemistry , organic chemistry , catalysis , biology , polyethylene glycol , ecology , physics , thermodynamics , finance , economics
PEG-600 was used as solvent to synthesize title compounds in one-pot, green and three component method. Compound 4a-e derivatives were obtained by a three-component reaction of Pyrrolopyridine ( 1 ), propargyl bromide ( 2 ) and 1-(azidomethyl)-4-halobenzene (3) which is an eco-friendly method.