Open AccessThe effect of leaching agent on molecularly imprinted membrane urea transport process based on polyeugenoxy acetic acid
Author(s) -
Muhammad Cholid Djunaidi,
Tri Wahyuni,
Retno Ariadi Lusiana,
Didik Setiyo Widodo,
Pardoyo Pardoyo
Publication year - 2020
Publication title -
iop conference series. materials science and engineering
Language(s) - English
Resource type - Journals
eISSN - 1757-899X
pISSN - 1757-8981
DOI - 10.1088/1757-899x/959/1/012023
Subject(s) - urea , membrane , chemistry , nuclear chemistry , acetic acid , citric acid , inorganic chemistry , organic chemistry , biochemistry
Research on membrane synthesis as a hemodialysis membrane candidate has been carried out with molecular imprinting technique using MIM (Molecularly Imprinted Membrane) based on polyeugenoxy acetic acid. Polieugenoxy acetic acid was obtained from the synthesis of eugenol derivatives. This research aims to produce a selective urea membrane based on polyeugenoxy acetic acid for hemodialysis process and to know the effect of different leaching agents in the template release in the transport test. Polyeugenoxy acetic acid that has been bound with urea was mixed with Poly Vinyl Alcohol (PVA), a crosslinking agent for Poly Ethylene Glycol Diglycidyl Ether (PEGDE), and N-Methyl 2 Pyrrolidone solvent (NMP) to form the hydrogel. The hydrogel was then dissolved by NMP to make a membrane. The process of releasing the urea template used ethanol and HCl to obtain urea MIM (Molecularly Imprinted Membrane ) and transports was done to find out the difference in membrane transportability. The polymer base and urea MIM obtained were characterized using FTIR, SEM-EDX, and TGA / DTA, while urea MIM was used to transport urea, creatinine, and vitamin B12 through the transport process and was analyzed by UV-VIS spectrophotometer. The results obtained are that MIM has better transports results than NIM. The percentage of transport of urea, creatinine, and vitamin B12 by MIM membranes is 45.02%; 33.63%; 14.28%, and the percentage of transport of urea, creatinine, and vitamin B 12 by NIM membranes was 43.36%; 27.42%; 9.9%. In addition, there is an influence of eluent variations (leaching agent) on the transport of urea, creatinine, and vitamin B 12 , where the optimum transport results are shown in washing using HCl eluents. Percentage of urea transport by membrane washed with eluent variations of HCl, Ethanol, and Aquadest was 45.02%; 40.12%; 39.17%, the percentage of creatinine transport in HCl, Ethanol, and Aquadest variations was 47.03%; 44.2%; 36.6%, and the percentage of vitamin B 12 transport in the HCl, Ethanol and Aquadest variations respectively was 8.87%; 18.27%; 3.65%.