Open AccessStudy Of The Effect Of Stimulative Properties Of Alloxan - Thiosemicarbazone Schiff’s Base Ligand Synthesised In An Eco Friendly Manner
Author(s) -
Padma Priya Gopalakrishnan,
Girija Chamarahalli Ramakrishna Iyer
Publication year - 2020
Publication title -
iop conference series. materials science and engineering
Language(s) - English
Resource type - Journals
eISSN - 1757-899X
pISSN - 1757-8981
DOI - 10.1088/1757-899x/955/1/012100
Subject(s) - semicarbazone , chemistry , schiff base , ligand (biochemistry) , ketone , antifungal , aldehyde , molecule , combinatorial chemistry , alloxan , stereochemistry , organic chemistry , receptor , biochemistry , biology , microbiology and biotechnology , endocrinology , catalysis , diabetes mellitus
Ligands are fascinating class of ions or molecule that binds to a central metal ion to form coordination compounds. Ligand ability to donate lone pair of electrons or capacity to act as “Lewis Bases” has created tremendous wave in pharmaceutical industry. Schiff’s bases are multifaceted class of compound formed by condensation of aldehyde or ketone with a primary amine under preliminary condition. The ligands are efficient enough to act as antibacterial, antiviral, anti-inflammatory, antifungal. Recent studies reveal their ability to exhibit antiproliferative, anticancer, anti oxidant properties is a signpost in drug chemistry. The present study focuses on the efficiency of environment friendly synthesized ligand Alloxan thiosemicarbazone which is screened for its antibacterial, antifungal, docking properties.