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Organic base catalysed synthesis of benzimidazole
Author(s) -
Sarah John,
G. Kavya,
M Aparna,
Rajagopal Krishnan,
R. Parvathy,
T. S. Sreenath,
Akhil Sivan
Publication year - 2020
Publication title -
iop conference series. materials science and engineering
Language(s) - English
Resource type - Journals
eISSN - 1757-899X
pISSN - 1757-8981
DOI - 10.1088/1757-899x/872/1/012142
Subject(s) - benzimidazole , catalysis , base (topology) , chemistry , combinatorial chemistry , reaction conditions , metal , organic chemistry , mathematics , mathematical analysis
A mild and effective protocol for benzimidazolesynthesis from o-phenylenediamine and aromatic aldehydes catalysed by DBU is described. The synthesized compounds find application in the pharmaceutical, dye and material science fields. Mild reaction conditions, low amount of chemicals and use of metal-free catalysts are the highlights of the reaction.

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