Open AccessGold nanorods and their nanocomposites based on polyurethane foam for determination of catecholamines in biological fluids
Author(s) -
M. V. Gorbunova,
V. V. Apyari,
А.В. Гаршев,
П. А. Волков,
V. V. Tolmacheva,
С. Г. Дмитриенко
Publication year - 2020
Publication title -
iop conference series. materials science and engineering
Language(s) - English
Resource type - Journals
eISSN - 1757-899X
pISSN - 1757-8981
DOI - 10.1088/1757-899x/848/1/012023
Subject(s) - nanorod , polyurethane , polystyrene , colloidal gold , nanocomposite , reagent , materials science , elution , nanoparticle , chromatography , chemical engineering , chemistry , nanotechnology , organic chemistry , composite material , polymer , engineering
Capability of gold nanorods and their nanocomposites based on polyurethane foam as spectrophotometric reagents for catecholamines determination was examined. Comparison of the analytical properties of the systems based on interaction of nanoparticles of different morphology with various reagents in the presence of catecholamines was carried out, gold nanorods-based system is characterized by the highest sensitivity. Applicability of gold nanorods and their nanocomposites for catecholamines determination in biological fluids (urine, serum) was proved by HPLC analysis. Catecholamines preconcentration by dynamic sorption on hypercrosslinked polystyrene and further elution with 6M acetic acid could serve to improve the sensitivity of the analysis.