Open Access
Facile synthesis of silver nanoparticles using leaf extract of Hyptis suaveolens (L.) Poit for environmental and biomedical applications
Author(s) -
Agbaje Lateef,
Suliat M. Oladejo,
P.O. Akinola,
Daniel Ayandiran Aina,
Lorika S. Beukes,
Bolaji I. Folarin,
E.B. Gueguim Kana
Publication year - 2020
Publication title -
iop conference series. materials science and engineering
Language(s) - English
Resource type - Journals
eISSN - 1757-899X
pISSN - 1757-8981
DOI - 10.1088/1757-899x/805/1/012042
Subject(s) - silver nanoparticle , chemistry , dpph , nuclear chemistry , aqueous solution , nanoparticle , biomolecule , traditional medicine , antioxidant , nanotechnology , biochemistry , organic chemistry , materials science , medicine
Aqueous leaf extract of Hyptis suaveolens was investigated to synthesize silver nanoparticles (Hs-AgNPs). Biomolecules such as phenolics, proteins, carbohydrates and esters facilitated bioformation of Hs-AgNPs with ƛmax at 420 nm. The nearly spherical Hs-AgNPs were polydispersed and sized 29.19-52.27 nm with yield of 85.8 %. Hs-AgNPs showed potent inhibition of 75.22-100 % against multidrug resistant bacteria, and fungal growth inhibition of 73.33-100 %. Hs-AgNPs scavenged DPPH and H 2 O 2 by 77.75-83.19, and 54.21-70.11 % respectively. It also effectively inhibited coagulation of blood. The study established the nanobiotechnological importance of H. suaveolens , with bioformation of AgNPs that have potent activities for environmental and biomedical applications.