Open AccessSpectrophotometric Determination of Tiopronin using 2,2’-Bipyridyl as Chromogenic Reagent
Author(s) -
Changqing Tu,
Wen Xi
Publication year - 2020
Publication title -
iop conference series. materials science and engineering
Language(s) - English
Resource type - Journals
eISSN - 1757-899X
pISSN - 1757-8981
DOI - 10.1088/1757-899x/729/1/012020
Subject(s) - tiopronin , chromogenic , reagent , absorbance , orange (colour) , chemistry , chromatography , organic chemistry , food science , medicine , pharmacology
The hydrosulfuryl(-SH) in tiopronin molecule has reducibility, and it can reduce Fe 3+ to Fe 2+ . We use 2,2’-bipyridyl as chromogenic reagent of Fe 2+ , Fe 2+ react with 2,2’-bipyridyl to form the orange red complex which the maximum absorption is at 522 nm. By measuring the absorbance of the orange red complex, the content of tiopronin can be determinated. A new method for the spectrophotometric determination of tiopronin has been established. The content of tiopronin is determinated using this method, and the results are satisfactory.