Open AccessSynthesis of calcium phosphate composite organogels by using castor oil and sorbitan monopalmitate based for dentine occlusion material
Author(s) -
Jutharat Waiyawat,
Khrongkhwan Akkarachaneeyakorn,
P. Changpongpan,
Mesayamas Kongsema,
Chayada Teanchai,
Orapin Chienthavorn
Publication year - 2019
Publication title -
iop conference series. materials science and engineering
Language(s) - English
Resource type - Journals
eISSN - 1757-899X
pISSN - 1757-8981
DOI - 10.1088/1757-899x/625/1/012024
Subject(s) - castor oil , thermogravimetric analysis , sorbitan , emulsion , calcium , nuclear chemistry , scanning electron microscope , chemistry , polyvinyl alcohol , materials science , phosphate , aqueous solution , aqueous two phase system , chemical engineering , organic chemistry , composite material , fatty acid , fatty acid ester , engineering
Calcium phosphate composite organogel was synthesized from a mixture of sorbitan monopalmitate as emulsifier and castor oil as oil phase at 60 °C to establish emulsion system with calcium chloride and di-sodium hydrogen phosphate aqueous solution as water phase. The heated mixture was cooled at room temperature to form organogel. The prepared organogels were investigated by thermogravimetric analysis (TGA), scanning electron microscope (SEM), transmission electron microscope (TEM) and cytotoxicity test. The prepared organogels of 4:3 and 1:1 in oil/water content ratio were white and gritty in nature, which resulted in calcium phosphate nanoparticles with spherical shape of 1.3 to 1.9 μm and 1.2 to 2.3 μm, respectively. They were able to successfully occlude into dentine tubules within 1 day. In addition, the prepared organogels were found to have acceptable toxicity level for daily human use with high concentration up to 1600 μg/ml. Hence, these organogels showed the promising results to be developed as an effective dentine occlusion material in relieving of dentin hypersensitivity.