Open AccessStudy on Chitosan tetrasaccharide monomer Recognition System Based on Molecular Imprinting Technology
Author(s) -
Meng Li,
Yingying Meng,
Y. Zheng
Publication year - 2019
Publication title -
iop conference series. materials science and engineering
Language(s) - English
Resource type - Journals
eISSN - 1757-899X
pISSN - 1757-8981
DOI - 10.1088/1757-899x/612/5/052021
Subject(s) - oxamide , chitosan , molecularly imprinted polymer , chemistry , monomer , molecule , molecular imprinting , zinc , molecular recognition , combinatorial chemistry , polymer chemistry , polymer , organic chemistry , selectivity , catalysis
In this paper, we use chitosan as template molecule and N-[2-(dimethylamino) ethyl]-N’-[(2-hydroxy-4-vinylphenyl)] oxamide (H3eoxdmpe) as bridge ligand and directionally synthesize N-[2-(dimethylamino) ethyl]-N’-[(2-hydroxy-4-vinylphenyl)] oxamide dinuclear zinc-chitosan [Zn 2 (eoxdmpe) (tetrachit)] (ClO 4 ) coordination monomer. We study the interaction between complex and template molecules by ultraviolet spectrophotometry and the recognition ability of complex to monosaccharide molecule quantitatively by formula. The crystal structures of N-[2-(dimethylamino) ethyl]-N’-(2-hydroxy-4-vinylphenyl)] oxamide binuclear zinc-chitosan complex are determined and analyzed by X-ray single crystal diffractive technique and the results show that the metal coordination bond is a favorable binding activity for chitosan. This study provides an ideal model for the construction of metal coordination molecularly imprinted polymers which are selectively recognized by chitosan.