Open AccessAntimicrobial activity of the novel metal oxide nanoparticles against selected human pathogenic bacteria
Author(s) -
S. Gnanam,
R. Ashokkumar,
K. SenthilKannan
Publication year - 2019
Publication title -
iop conference series. materials science and engineering
Language(s) - English
Resource type - Journals
eISSN - 1757-899X
pISSN - 1757-8981
DOI - 10.1088/1757-899x/561/1/012086
Subject(s) - silver nanoparticle , oxide , nuclear chemistry , cerium oxide , nanoparticle , proteus mirabilis , tin oxide , metal , chemistry , materials science , inorganic chemistry , escherichia coli , nanotechnology , organic chemistry , biochemistry , gene
Antibacterial activities of the selected metal oxide nanoparticles viz., lead oxide (PbO), silver oxide (Ag 2 O), tin oxide (SnO 2 ), alpha manganese sesquioxide (α–Mn 2 O 3 ), cerium oxide (CeO 2 ), silver doped tin oxide (Ag-SnO 2 ), silver doped alpha manganese sesquioxide (Ag-α–Mn 2 O 3 ), silver doped lead oxide (Ag-PbO) and silver doped cerium oxide (Ag-CeO 2 ) have been successfully investigated against human pathogens, viz., Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Proteus mirabilis. The antibacterial studies of the selected nanoparticles are primarily investigated by the well diffusion process. Different concentrations of the nanoparticles are analyzed by the minimal inhibitory concentration (MIC) technique. Among the metal oxide nanoparticles, the Ag-doped CeO 2 nanoparticles showed maximum inhibition against E.coli, followed by against P. aeruginosa, P. mirabilis and K. pneumoniae. Further, the MIC studies showed that, the Ag-CeO 2 nanoparticles exhibited maximum inhibition against human pathogenic bacteria.