Open AccessAntibacterial cream formulation of ethanolic Pliek U extracts and ethanolic residue hexane Pliek U extracts against Staphylococcus aureus
Author(s) -
R. Rahmad,
Nanda Earlia,
Caresya Insani Bangga Nabila,
Iin Inayati,
Mohamad Amin,
Crs Prakoeswa,
K Khairan,
Rinaldi Idroes
Publication year - 2019
Publication title -
iop conference series. materials science and engineering
Language(s) - English
Resource type - Journals
eISSN - 1757-899X
pISSN - 1757-8981
DOI - 10.1088/1757-899x/523/1/012011
Subject(s) - staphylococcus aureus , antibacterial activity , lauric acid , antimicrobial , traditional medicine , chemistry , residue (chemistry) , food science , hexane , ingredient , fatty acid , biology , bacteria , chromatography , medicine , biochemistry , organic chemistry , genetics
Indonesia as the largest archipelago country in the world is also known as a country with plenty of natural resources that can be used as traditional medicinal plants. Pliek U is a fermented crude coconut meat has been used as an ingredient in Aceh traditional food and also used as a traditional topical medicine in Aceh. Pliek U is potential as a source of free fatty acids (FFAs) such as lauric acid and monolauric acid which have antimicrobial properties. The aim of this study is to determine the activity ethanolic Pliek U extracts (EPUE) and ethanolic of residue hexane of Pliek U extracts (ERHPUE) and also the activities of their cream formulation against Staphylococcus aureus The antibacterial activity was determined by disc difussion method with clindamycin as a positive control. The antibacterial activity results showed that EPUE has antibacterial activity against Staphylococcus aureus with diameter inhibition zone of 8.66±0.57 mm, while ERHPUE and their cream have no activity against Staphylococcus aureus .