Open AccessCentral Composite Design for Solvent Extraction of Oil from Neem (Azadirachta indica) seed
Author(s) -
M. E. Ojewumi,
Adegboyega B. Ehinmowo,
G.P. Ekanem,
J. U. Nsionu,
E. O. Bolujo
Publication year - 2021
Publication title -
iop conference series. materials science and engineering
Language(s) - English
Resource type - Journals
eISSN - 1757-899X
pISSN - 1757-8981
DOI - 10.1088/1757-899x/1107/1/012109
Subject(s) - azadirachta , neem oil , central composite design , extraction (chemistry) , extractor , chromatography , solvent , hexane , soxhlet extractor , meliaceae , chemistry , mathematics , response surface methodology , materials science , botany , engineering , biology , process engineering , organic chemistry
Optimization of neem oil extraction using Central Composite Design (CCD) was evaluated in this research. The effects of two factors: sample weight and extraction duration on the response which is neem oil volume extracted, were investigated. The CCD employed resulted in 13 experimental runs. Extraction was carried out in a 250 ml Soxhlet extractor. Hexane was used as solvent with thermostated heating mantle at temperature 60°C. Results obtained shows the optimized values of 54.69% of neem oil was obtained with 25 g weight of sample with extraction time of 12hours. The r 2 and r 2 adj values were close to 1 which indicates that the regression model was a good one.