Open AccessSynthesis, complexation properties, antimicrobial and anticoagulant activity of 2-{3-[4-(dimethylamino)phenyl]-1-hydroxyprop-2-en-1-ylidene}-4-nitro-1H-indene-1,3(2H)-dione
Author(s) -
I. Nikolova,
I. Kostova,
M. Staneva,
Marin Marinov
Publication year - 2021
Publication title -
iop conference series. materials science and engineering
Language(s) - English
Resource type - Journals
eISSN - 1757-899X
pISSN - 1757-8981
DOI - 10.1088/1757-899x/1031/1/012112
Subject(s) - chemistry , indene , antimicrobial , nitro , derivative (finance) , proton nmr , medicinal chemistry , stereochemistry , combinatorial chemistry , organic chemistry , alkyl , financial economics , economics
This article presents the synthesis of a new 4-nitro-cinnamoyl derivative of 2-acyl-1,3-indandione. The resulting compound was subjected to interaction with ErCl3x6H2O, which was obtained from Er2O3 and HCl. The synthesized compounds were proven by IR and NMR spectroscopy. The spectral data clearly proves the formation of a chelate complex. A probable structural formula of the coordination compound is also proposed. The obtained compounds were used for analysis of their antimicrobial and anticoagulant activity.