Open AccessOptimization of the pH of mosquito repellent from citronella using response surface methodology
Author(s) -
Prima Astuti Handayani,
Dhoni Hartanto,
Willy Tirza Eden,
D F Anyelir,
G R H H Salsabila
Publication year - 2022
Publication title -
iop conference series. earth and environmental science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.179
H-Index - 26
eISSN - 1755-1307
pISSN - 1755-1315
DOI - 10.1088/1755-1315/969/1/012050
Subject(s) - response surface methodology , citronellol , central composite design , stearic acid , chemistry , chromatography , alcohol , pulp and paper industry , essential oil , geraniol , organic chemistry , engineering
Citronella is a source of essential oil obtained from steam distillation. The production of citronella oil is quite high; therefore, it can be applied in various fields. One of its applications is as an active substance in mosquito repellent creams. The citronella oil used in this study contained 11.59% citronellol content at a retention time of 16.544 minutes and citronellol content of 14.78% at a retention time of 27.165 minutes using the Gas Chromatography Mass Spectrometry method. In the manufacture of mosquito repellent creams, there are still mismatches in the composition between variables, so there is a need for optimization in this study. Optimization in this study using Response Surface Methodology model Central Composite Design on Statistica 10 software with 19 treatments. The method used was the addition of independent variables, citronella oil (2-4%), stearic acid (10-16%) and cetyl alcohol (4-6%) processed using the RSM-CCD method to determine the optimum pH. Optimization results with RSM at pH resulted in optimum conditions for citronella oil content of 2.1591%, stearic acid 18.045% and cetyl alcohol 6.6818% with a pH of 6.1.