Open AccessTwenty weeks of Centella asiatica improved cognitive function of women elderly with dementia
Author(s) -
Lisna Anisa Fitriana,
Kusnandar Anggadiredja,
Setiawan Setiawan,
I Ketut Adnyana
Publication year - 2021
Publication title -
iop conference series. earth and environmental science
Language(s) - English
Resource type - Journals
eISSN - 1755-1307
pISSN - 1755-1315
DOI - 10.1088/1755-1315/755/1/012064
Subject(s) - centella , dementia , verbal fluency test , cognition , placebo , medicine , fluency , audiology , memory span , psychology , working memory , psychiatry , traditional medicine , neuropsychology , disease , alternative medicine , mathematics education , pathology
Centella asiatica is known to improve cognitive function, but its influence on several domains of cognitive function in dementia women is still limited. This study aimed to determine the effect of Centella asiatica on cognitive function in women elderly with dementia. Screening for dementia used an MMSE questionnaire (Mini-Mental State Examination) with a cut off of 23. The trial comprised the two groups: Centella Asiatica group (CAG) 1x500 mg/day and placebo control group (PCG) 1x500 mg/day. Thirty-nine women were included in this study with mean age 74 ± 10.05. The results showed that the CAG group was effective in increasing the semantic fluency domain (p < 0.001) and visual memory (p < 0.001) compared to PCG. Meanwhile, the phonemic fluency domain and the forward-backward digit span did not show a significant difference compared to the placebo control group. In conclusion, administration of Centella asiatica for 20 weeks is effective in increasing semantic fluency and visual memory in women elderly with dementia.