Open AccessThe effectiveness of various antibacterial drugs in the treatment of swine respiratory diseases
Author(s) -
I. M. Kugelev,
N. A. Kapay,
O V Davydenkova,
A S Russkin
Publication year - 2021
Publication title -
iop conference series. earth and environmental science
Language(s) - English
Resource type - Journals
eISSN - 1755-1307
pISSN - 1755-1315
DOI - 10.1088/1755-1315/723/2/022065
Subject(s) - enterobacter cloacae , morganella morganii , klebsiella pneumoniae , microbiology and biotechnology , enterobacter aerogenes , pseudomonas aeruginosa , azithromycin , medicine , antibiotics , klebsiella , enterococcus faecalis , klebsiella oxytoca , biology , florfenicol , staphylococcus aureus , bacteria , escherichia coli , biochemistry , genetics , gene
The polyethiological nature of pig respiratory diseases involves the use of antibacterial drugs of the widest possible spectrum of action. The success of the whole range of therapeutic measures will largely depend on the choice of antibacterial drugs. This article presents the results of a clinical (field) study evaluating the effectiveness of azithromycin, florfenicol and amoxicillin in respiratory diseases of pigs under conditions of contamination with associates of highly resistant pathogens ( Mycoplasma spp., Hemolytic coagulase-positive Staph.aureus, non-hemolytic Lac-coli fermenting E. hemolytic Enterococcus faecalis, Klebsiella pneumoniae, Klebsiella oxytoca, Morganella morganii, Pseudomonas aeruginosa, Proteus mirabillis, Enterobacter aerogenes, Enterobacter cloacae ). The study included 90 crossbred piglets 100-110 days old with pronounced clinical signs of respiratory diseases. In the course of the work, the dynamics of changes in the state of piglets was assessed: the rate of disappearance of clinical signs, the average daily weight gain, the presence of associates of highly resistant microorganisms after a course of treatment, the mortality rate and the number of adverse events and side reactions. The results of the study revealed the formation of multidrug resistance in a number of pathogens. Preparations based on florfenicol and azithromycin showed higher therapeutic efficacy in the treatment of respiratory diseases of piglets under conditions of contamination of associates of highly resistant pathogens.