Open AccessAntibiotics susceptibility on Salmonella typhi isolates from typhoid fever patients
Author(s) -
Hadeel A. Hassan Alhayli,
Azhar Ammran AL-Thahab
Publication year - 2021
Publication title -
iop conference series. earth and environmental science
Language(s) - English
Resource type - Journals
eISSN - 1755-1307
pISSN - 1755-1315
DOI - 10.1088/1755-1315/722/1/012021
Subject(s) - typhoid fever , ciprofloxacin , salmonella typhi , ceftriaxone , nalidixic acid , amikacin , azithromycin , salmonella , antibiotics , microbiology and biotechnology , cefotaxime , medicine , antibiotic resistance , tetracycline , blood culture , drug resistance , biology , bacteria , biochemistry , genetics , escherichia coli , gene
This study was conducted in Babylon province in the period from January 2019 to April 2019. Patients were randomly selected from Al-Musayyib General Hospital and Marjan Medical city,a clinics and laboratories in the Musayyib of Babylon province for patients suspected of typhoid fever, according to the diagnosis of the specialist physician.The result of the study showed some of the samples that have been culture were negative result, while the sample which gave a positive result for Salmonella typhi isolates were25 isolates as the ratio from blood sample 20 ( 13.3 % ), the rates of urine culture was 1 isolate ( 1.04%) while the rate of stool culture was 4( 11.7 % ). This study was proceed to show and compare the effect of many antibiotics with different mechanism of action and different families on the bacterial isolates of Salmonella typhi , the result show the most powerful effect of antibiotic is for imipenm which have strong sensitivity to this microorganism with the least bacterial resistance of 16 % percentage. The amikacin, chloramphphinicol and azithromycin show great bacterial sensitivity with low bacterial resistance percentage as 24, 28, 28 respectively, in another hand of cefotaxime, nalidixic acid, ciprofloxacin, ceftriaxone, tetracycline and trimethoprim / sulphaethoxazole are show very low bacterial sensitivity with great bacterial resistance as 96%, 92%, 88%, 84%,68 %, 56% respectively.Also all bacterial isolates were MDRTF characterized by resistance too at least one agent in three or more antibiotic categories