Open AccessFunctionalized Selenium-Doped Carbon Quantum Dots for Targeting Detection of Reactive Oxygen Species in Live Cells
Author(s) -
Di Zhou,
Hong Huang,
Yan Wang,
Junrong Yu,
Zuming Hu
Publication year - 2021
Publication title -
iop conference series. earth and environmental science
Language(s) - English
Resource type - Journals
eISSN - 1755-1307
pISSN - 1755-1315
DOI - 10.1088/1755-1315/692/3/032066
Subject(s) - organelle , reactive oxygen species , selenium , fluorescence , quantum dot , carbon fibers , nanotechnology , oxygen , chemistry , molecule , materials science , doping , biophysics , biochemistry , biology , optoelectronics , organic chemistry , physics , quantum mechanics , composite number , composite material
Selenium doped carbon quantum dots (Se-CQDs) are synthesized by a facile hydrothermal process. The Se-CQDs show narrow size distribution in the range of 3-4 nm, good optical properties, and high sensitivity in detection of various reactive oxygen species (ROS) as revealed by several characterizations. The Se-CQDs are then modified by three kinds of organelle targeting molecules with the aim of targeting detection of ROS in specific organelles. The confocal fluorescence studies on modified Se-CQDs and commercial organelle marker demonstrate the successful targeting detection of ROS in different organelles by our specific modified Se-CQDs.