
The drug Diprokarb for treatment of idiopathic babesial disease in dogs under the conditions of Russia
Author(s) -
Е. С. Беломытцева,
Р Т Сафиуллин,
М. В. Арисов
Publication year - 2021
Publication title -
iop conference series. earth and environmental science
Language(s) - English
Resource type - Journals
eISSN - 1755-1307
pISSN - 1755-1315
DOI - 10.1088/1755-1315/677/4/042013
Subject(s) - drug , medicine , disease , veterinary medicine , clinical disease , propionate , pharmacology , physiology , biology , biochemistry
Study of efficiency of the drug diprokarb with major active ingredient of imidocarb propionate was conducted. One milliliter of diprokarb contains 120 mg of imidocarb propionate. It was studied under the conditions of Moscow and Moscow Region using an example of spontaneous infestation of dogs with babesial disease. All studies were conducted at veterinary clinics using laboratory studies of the blood of infected animals, as well as the study of ixodic ticks that are the major carriers. Monitoring of physical status of animals was being performed from time of the first appearance of babesial disease clinical signs to the complete disappearance of hematozoons from the blood, as well as products of their vital activity. Studies of the animals, which are not demonstrated evident clinical signs of infection, were also conducted during ixodic ticks’ season of activity. Diprokarb was used as the main drug and the symptomatic therapy was conducted when disease is identified. The drug demonstrated 100 % efficiency when applied at the dose of 6 mg per kg of animal body weight.