Larvicidal Activity of Bintaro (Cerbera odollam) against Culex quinquefasciatus

Mosquitoes are known for their bites which caused discomfort and its role as vector for various dangerous diseases that has been the bane of humanity since antiquity. One of them is Culex quinquefasciatus which facilitates the spread of arbovirus and nematodes that caused debilitating impact for human life. To eliminate mosquito, the study for evaluating plant-based mosquito larvicidal extract of Cerbera odollam extract against C. quinquefasciatus was conducted. Twenty-five second instar of C. quinquefasciatus were subjected to the crude and fractionated extracts of C. odollam , and the larval mortality was observed at 24, and 48 h of exposure. The results showed that the crude extracts of leaves, rinds, and stem bark exhibited low larvicidal activities. Interestingly, crude extract of the seed kernel exhibited high larvicidal activity. We found that the fractionated extract derived from the seed kernel extract using ethyl acetate and n-hexane exhibited high larvicidal activities, suggesting that C. odollam extract could be promoted as a material for larval control.