Open AccessSubcritical water extraction of Diosgenin from Dioscorea nipponica Makino and its antioxidant activity
Author(s) -
Wenying Zhao,
Hao-Qi Hao,
Wei Xiao,
Quangang Zhu
Publication year - 2020
Publication title -
iop conference series. earth and environmental science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.179
H-Index - 26
eISSN - 1755-1307
pISSN - 1755-1315
DOI - 10.1088/1755-1315/559/1/012004
Subject(s) - diosgenin , extraction (chemistry) , antioxidant , chemistry , dioscorea , water extraction , high performance liquid chromatography , chromatography , yield (engineering) , traditional medicine , food science , biochemistry , materials science , organic chemistry , medicine , alternative medicine , pathology , metallurgy
Subcritical water extraction (SWE) was used as an alternative and environmentally friendly method for extraction of diosgenin from Dioscorea nipponica Makino (DNM). The effects of extraction temperature (75–175 °C) and time (15–45 min) on the diosgenin yield and antioxidant activity of extracts from DNM were analyzed. The profiles of extraction compounds at different temperatures were determined by HPLC. Results showed that diosgenin extraction was significantly ( P < 0.05) affected by the extraction time and temperature and their interaction. The antioxidant activity was also affected by treatment time and temperature. The high antioxidant capacity was correlated with the high diosgenin content. Subcritical water may be a potential medium for diosgenin production.